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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ZNF189 Antibodies

          Invitrogen

          ZNF189 Polyclonal Antibody

          View all (4) ZNF189 antibodies

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          Cite ZNF189 Polyclonal Antibody

          • Antibody Testing Data (3)
          ZNF189 Antibody in Immunocytochemistry (ICC/IF)
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          ZNF189 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          ZNF189 Antibody (PA5-57073) in ICC/IF

          Immunofluorecent analysis of ZNF189 in human cell line U-2 OS using ZNF189 Polyclonal Antibody (Product # PA5-57073). Staining shows positivity in intermediate filaments and aggresome. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          ZNF189 Antibody in Immunocytochemistry (ICC/IF)
          ZNF189 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ZNF189 Antibody in Western Blot (WB)
          ZNF189 Polyclonal Antibody

          Product Details

          PA5-57073

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human ZNF189. Recombinant protein control fragment (Product #RP-97597).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2649987

          Product Specific Information

          Immunogen sequence: KDEEPTVKQE IEEIEEEVEP QGVIVTRIKS EIDQDPMGRE TFELVGRLDK QRGIFLWEIP RESLTQEQRM FRENTNIIRK RPN

          Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 80%.

          Target Information

          Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Zinc finger protein 189

          View more View less

          Gene Aliases: ZNF189

          View more View less

          UniProt ID: (Human) O75820

          View more View less

          Entrez Gene ID: (Human) 7743

          View more View less

          Function(s)
          DNA binding transcription factor activity, sequence-specific DNA binding metal ion binding DNA-binding transcription factor zinc finger transcription factor C2H2 zinc finger transcription factor gene-specific transcriptional regulator
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter positive regulation of defense response to virus by host transcription, DNA-templated mitophagy in response to mitochondrial depolarization xenophagy
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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