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Invitrogen
CGGBP1 Polyclonal Antibody
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Product Details
PA5-57317
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CGGBP1. Recombinant protein control fragment (Product #RP-96392).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MERFVVTAPP ARNRSKTALY VTPLDRVTEF GGELHEDGGK LFCTSCNVVL NHVRKSAISD HLKSKTHTKR KAEFEEQNVR K
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 20 kDa CGG-binding protein; CGG triplet repeat-binding protein 1; CGG-binding protein 1; CGGBP1; p20-CGG binding protein; p20-CGGBP DNA-binding protein
Gene Aliases: AA960172; AL023996; AW045841; CGGBP; CGGBP1; p20-CGGBP
UniProt ID: (Human) Q9UFW8, (Mouse) Q8BHG9
Entrez Gene ID: (Human) 8545, (Rat) 288353, (Mouse) 106143
DNA binding
double-stranded DNA binding
protein binding
identical protein binding
DNA-binding transcription factor binding
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
regulation of gene expression
regulation of gene expression, epigenetic
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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