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Invitrogen
DNAJB2 Polyclonal Antibody
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Product Details
PA5-57590
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DNAJB2. Recombinant protein control fragment (Product #RP-96083).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LTGTGTGPSR AEAGSGGPGF TFTFRSPEEV FREFFGSGDP FAELFDDLGP FSELQNRGSR HSGPFFTFSS SFPGHSDFSS SSFSFSPGAG AFRSVS
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.
Target Information
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. Two isoforms are produced due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DnaJ (Hsp40) homolog, subfamily B, member 2; DnaJ homolog subfamily B member 2; dnaJ protein homolog 1; Heat shock 40 kDa protein 3; Heat shock protein J1; heat shock protein, neuronal DNAJ-like 1; HSJ-1
Gene Aliases: CMT2T; DNAJB2; DSMA5; HSJ-1; HSJ1; HSPF3
UniProt ID: (Human) P25686
Entrez Gene ID: (Human) 3300
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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