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Invitrogen
MORC1 Polyclonal Antibody
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Product Details
PA5-57647
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MORC1. Recombinant protein control fragment (Product #RP-96304).
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LSSFELSASR RGQKRNIEET DSDVEYISET KIMKKSMEEK MNSQQQRIPV ALPENVKLAE RSQRSQIANI TTVWRAQPTE GCLKNAQAAS WEMKRKQ
Highest antigen sequence identity to the following orthologs: Mouse - 31%, Rat - 30%.
Target Information
This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cancer/testis antigen 33; CT33; microrchidia, mouse, homolog of; MORC family CW-type zinc finger protein 1; unnamed protein product
Gene Aliases: CT33; MORC; MORC1; ZCW6
UniProt ID: (Human) Q86VD1
Entrez Gene ID: (Human) 27136
behavioral fear response
spermatogenesis
negative regulation of gene expression
cell differentiation
gene silencing by RNA
transposition, RNA-mediated
regulation of gene expression, epigenetic
DNA demethylation of male pronucleus
transposable element silencing by heterochromatin formation
negative regulation of DNA-templated transcription, initiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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