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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KEGNEMEGEE LDPLDAYMEE VKEEVKKFNM RSVKGGGGNE KKSGPTVTKV VTVVTTKKAV VDSDKKKGEL MENDQDAM
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DEAD box protein 46; Probable ATP-dependent RNA helicase DDX46; PRP5 homolog
Gene Aliases: DDX46; KIAA0801
Entrez Gene ID: (Human) 9879
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