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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • DDX21 Antibodies

          Invitrogen

          DDX21 Polyclonal Antibody

          Advanced Verification
          View all (13) DDX21 antibodies

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          Cite DDX21 Polyclonal Antibody

          • Antibody Testing Data (5)
          • Advanced Verification (2)
          DDX21 Antibody in Immunocytochemistry (ICC/IF)
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          DDX21 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          DDX21 Antibody (PA5-57734) in ICC/IF

          Immunofluorecent analysis of DDX21 in human cell line U-2 OS using DDX21 Polyclonal Antibody (Product # PA5-57734). Staining shows localization to nucleoli. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          DDX21 Antibody in Immunocytochemistry (ICC/IF)
          DDX21 Antibody in Immunohistochemistry (IHC)
          DDX21 Antibody in Immunohistochemistry (IHC)
          DDX21 Antibody in Immunohistochemistry (IHC)
          DDX21 Antibody in Western Blot (WB)
          DDX21 Antibody
          DDX21 Antibody
          DDX21 Polyclonal Antibody

          Product Details

          PA5-57734

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human DDX21. Recombinant protein control fragment (Product #RP-102727).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2640464

          Product Specific Information

          Immunogen sequence: DSRRWQLSVA TEQPELEGPR EGYGGFRGQR EGSRGFRGQR DGNRRFRGQR EGSRGPRGQR SGGGNKSNRS QNKGQKRSFS KAFGQ

          Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 82%.

          Target Information

          Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: DEAD (Asp-Glu-Ala-Asp) box helicase 21; DEAD (Asp-Glu-Ala-Asp) box polypeptide 21; DEAD box protein 21; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 21; Gu protein; Gu-alpha; Nucleolar RNA helicase 2; Nucleolar RNA helicase Gu; Nucleolar RNA helicase II; RH II/Gu; RNA helicase II/Gu alpha

          View more View less

          Gene Aliases: DDX21; GUA; GURDB; RH-II/GU; RH-II/GuA

          View more View less

          UniProt ID: (Human) Q9NR30

          View more View less

          Entrez Gene ID: (Human) 9188

          View more View less

          Function(s)
          double-stranded RNA binding ATP-dependent RNA helicase activity protein binding ATP binding rRNA binding snoRNA binding poly(A) RNA binding 7SK snRNA binding
          Process(es)
          osteoblast differentiation rRNA processing transcription from RNA polymerase II promoter response to virus RNA secondary structure unwinding response to exogenous dsRNA positive regulation of gene expression, epigenetic
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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