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Invitrogen
QARS Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-57902
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human QARS. Recombinant protein control fragment (Product #RP-96456).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HTGYVIELQH VVKGPSGCVE SLEVTCRRAD AGEKPKAFIH WVSQPLMCEV RLYERLFQHK NPEDPTEVPG GFLSDLNLAS LHVVDA
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 100%.
Target Information
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glutamine-tRNA ligase; glutamine-tRNA synthetase; unnamed protein product
Gene Aliases: 1110018N24Rik; 1200016L19Rik; GLNRS; MSCCA; PRO2195; QARS; RGD1562301
UniProt ID: (Human) P47897, (Mouse) Q8BML9, (Rat) Q66H61
Entrez Gene ID: (Human) 5859, (Mouse) 97541, (Rat) 290868
translation
tRNA aminoacylation for protein translation
glutaminyl-tRNA aminoacylation
brain development
negative regulation of stress-activated MAPK cascade
tRNA aminoacylation
negative regulation of transcription, DNA-templated
negative regulation of apoptotic signaling pathway
negative regulation of apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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