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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: DTEILKVART HHVQAESYLV YNIMSSGEIE CSNTLEDELD QALPSQAFIY RPIRQRVYSL LLEDCQDVTS TCLAVKEWFV YPGNPL
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 83%.
The transcription factor peroxisome proliferator-activated receptor -gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alternatively spliced; constitutive coactivator of PPAR-gamma; f120b; family with sequence similarity 120B; nuclear receptor coactivator; PPARG constitutive coactivator 1; PPARgamma constitutive coactivator 1; senataxin-associated nuclease 1; unnamed protein product
Gene Aliases: CCPG; dJ894D12.1; KIAA1838; PGCC1; SAN1
UniProt ID: (Human) Q96EK7
Entrez Gene ID: (Human) 84498
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