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Immunogen sequence: KRCQYEPDYR DNCGVTALMD AIQCGHIDVA RLLLDEHGAC LSAEDSLGAQ ALHRAAVTGQ DEAIRFLVSE LGVDVDVRAT STHLTA
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%.
Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ankyrin repeat domain-containing protein 16
Gene Aliases: ANKRD16
UniProt ID: (Human) A6NEF0
Entrez Gene ID: (Human) 54522
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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