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Invitrogen
GCP5 Polyclonal Antibody
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Product Details
PA5-58756
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GCP5. Recombinant protein control fragment (Product #RP-98101).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DWGKYLMEDE EMDIGPYMDT PNWSEESEEE NDQQPLSRED SGIQVDRTPL EEQDQNRKLD PCISWKDEPD DRSWLEHHVV HQYWTARPSQ FPHSLHLHSN LAAVW
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 76%.
Target Information
The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP5 ( gamma-Tubulin complex component 5), also known as TUBGCP5, is a 1, 024 amino acid member of the gamma-Tubulin complex and is highly expressed in heart and skeletal muscle. Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior and lower intellectual ability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gamma-tubulin complex component 5; gamma-tubulin complex component GCP5; GCP-5; tubulin, gamma complex associated protein 5
Gene Aliases: GCP5; KIAA1899; TUBGCP5
UniProt ID: (Human) Q96RT8
Entrez Gene ID: (Human) 114791
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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