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Invitrogen
ACSL6 Polyclonal Antibody
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Product Details
PA5-59191
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ACSL6. Recombinant protein control fragment (Product #RP-89595).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RYIINTADIS TVIVDKPQKA VLLLEHVERK ETPGLKLIIL MDPFEEALKE RGQKCGVVIK SMQAVEDCGQ ENHQAPVPPQ PDDLSIVCFT SGTTGNPKGA MLTHGNVVAD F
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%.
Target Information
FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5;12)(q31;p13) that involves ETV6 and ACSL6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Arachidonate--CoA ligase; fatty-acid-Coenzyme A ligase, long-chain 6; L LACS5; LACS 6; long fatty acyl-CoA synthetase 2; Long-chain acyl-CoA synthetase 6; Long-chain-fatty-acid--CoA ligase 6
Gene Aliases: ACS2; ACSL6; FACL6; KIAA0837; LACS 6; LACS2; LACS5
UniProt ID: (Human) Q9UKU0
Entrez Gene ID: (Human) 23305
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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