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          • Primary Antibodies ›
          • GLCE Antibodies

          Invitrogen

          GLCE Polyclonal Antibody

          View all (5) GLCE antibodies

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          Cite GLCE Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (5)
          GLCE Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          GLCE Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          GLCE Antibody (PA5-59194) in ICC/IF

          Immunofluorecent analysis of GLCE in human cell line U-2 OS using GLCE Polyclonal Antibody (Product # PA5-59194). Staining shows localization to mitochondria. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          GLCE Antibody in Immunocytochemistry (ICC/IF)
          GLCE Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GLCE Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GLCE Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GLCE Antibody in Immunohistochemistry (IHC)
          GLCE Polyclonal Antibody

          Product Details

          PA5-59194

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human GLCE. Recombinant protein control fragment (Product #RP-98073).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Amount

          30 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2642026

          Product Specific Information

          Immunogen sequence: SDKAIQFPRR SSSGFRVDGF EKRAAASESN NYMNHVAKQQ SEEAFPQEQQ KAPPVVGGFN SNVGSKVLGL KYEEIDCLIN DEHTIKGRRE GNEVFLPFTW VEKYFDVYGK VVQYDGYDR

          Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.

          Target Information

          Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: D-glucuronyl C5-epimerase; glucuronyl C5-epimerase; Heparan sulfate C5-epimerase; heparan sulfate epimerase; heparin/heparan sulfate-glucuronic acid C5-epimerase; Heparin/heparan sulfate:glucuronic acid C5-epimerase; Heparosan-N-sulfate-glucuronate 5-epimerase; Hsepi; UDP-glucuronic acid epimerase; unnamed protein product

          View more View less

          Gene Aliases: GLCE; HSEPI; KIAA0836

          View more View less

          UniProt ID: (Human) O94923

          View more View less

          Entrez Gene ID: (Human) 26035

          View more View less

          Function(s)
          calcium ion binding isomerase activity racemase and epimerase activity, acting on carbohydrates and derivatives protein homodimerization activity metal ion binding heparosan-N-sulfate-glucuronate 5-epimerase activity
          Process(es)
          positive regulation of cell proliferation heparan sulfate proteoglycan biosynthetic process heparin biosynthetic process negative regulation of cell projection organization positive regulation of SMAD protein import into nucleus
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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