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Invitrogen
NIPBL Polyclonal Antibody
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Product Details
PA5-59316
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Delangin Isoform A. Recombinant protein control fragment (Product #RP-96947).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TEEEERLWRD LIMERVTKSA DACLTTINIM TSPNMPKAVY IEDVIERVIQ YTKFHLQNTL YPQYDPVYRL DPHGGGLLSS KAKRAKCS
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.
Target Information
Probably plays a structural role in chromatin. Involved in sister chromatid cohesion, possibly by interacting with the cohesin complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Delangin; DKFZp434L1319; FLJ11203; FLJ12597; FLJ13354; FLJ13648; Nipped-B homolog; Nipped-B-like protein; SCC2 homolog; sister chromatid cohesion 2 homolog; unnamed protein product
Gene Aliases: CDLS; CDLS1; IDN3; IDN3-B; NIPBL; SCC2
UniProt ID: (Human) Q6KC79
Entrez Gene ID: (Human) 25836
mitotic sister chromatid segregation
negative regulation of transcription from RNA polymerase II promoter
metanephros development
heart morphogenesis
outflow tract morphogenesis
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
mitotic sister chromatid cohesion
brain development
heart development
sensory perception of sound
protein localization
regulation of gene expression
establishment of mitotic sister chromatid cohesion
maintenance of mitotic sister chromatid cohesion
somatic stem cell population maintenance
embryonic forelimb morphogenesis
forelimb morphogenesis
external genitalia morphogenesis
positive regulation of multicellular organism growth
ear morphogenesis
regulation of hair cycle
fat cell differentiation
positive regulation of ossification
positive regulation of transcription from RNA polymerase II promoter
regulation of embryonic development
embryonic digestive tract morphogenesis
embryonic organ morphogenesis
digestive tract development
developmental growth
eye morphogenesis
regulation of developmental growth
embryonic cranial skeleton morphogenesis
embryonic viscerocranium morphogenesis
cognition
face morphogenesis
gall bladder development
uterus morphogenesis
establishment of protein localization to chromatin
cellular response to X-ray
chromatin looping
replication-born double-strand break repair via sister chromatid exchange
positive regulation of neuron migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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