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Invitrogen
TLX2 Polyclonal Antibody
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Product Details
PA5-59372
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TLX2. Recombinant protein control fragment (Product #RP-98392).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GIDQILSGPE TPGGGLGLGR GGQGHGENGA FSGGYHGASG YGPAGSL
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 74%.
Target Information
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box 11-like 1; homeobox 11-like1; Homeobox protein Hox-11L1; Neural crest homeobox protein; T-cell leukemia homeobox protein 2
Gene Aliases: HOX11L1; NCX; TLX2
UniProt ID: (Human) O43763
Entrez Gene ID: (Human) 3196
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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