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Invitrogen
SNX33 Polyclonal Antibody
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Product Details
PA5-59378
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SNX33. Recombinant protein control fragment (Product #RP-98138).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VRSGVEAFIL GDVPMMAKIA ETYSIEMGPR GPQWKANPHP FACSVEDPTK QTK
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
SNX33 (sorting nexin-33), also known as SH3PX3, SH3PXD3C or SNX30, is a 574 amino acid protein that interacts with ADAM15 and FAS-L. Belonging to the sorting nexin family, SNX33 contains one BAR domain, one PX (phox homology) domain and one SH3 domain. The gene that encodes SNX33 consists of over 14,000 bases and maps to human chromosome 15q24.2. Housing approximately 106 million base pairs and encoding more than 700 genes, chromosome 15 makes up about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SH3 and PX domain containing 3; SH3 and PX domain-containing protein 3; SNX30; Sorting nexin-33
Gene Aliases: SH3PX3; SH3PXD3C; SNX30; SNX33
UniProt ID: (Human) Q8WV41
Entrez Gene ID: (Human) 257364
mitotic cell cycle
mitotic cytokinesis
intracellular protein transport
endocytosis
endosome organization
positive regulation of catabolic process
protein transport
endosomal transport
protein import
cleavage furrow formation
macropinocytosis
negative regulation of endocytosis
positive regulation of membrane protein ectodomain proteolysis
cell division
membrane tubulation
negative regulation of protein localization to cell surface
positive regulation of protein localization to cell surface
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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