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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LGPHNPTPPP SLDMFAEELA EEELETPTPT QRGEAESRGD GLVDVMWEYK WENTGDAELY GPFTSAQMQT WVSEGYFPDG VYCRKLDPPG GQFYNSKRID FDLY
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 89%.
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; U5 snRNP 52K protein; U5-52K
Gene Aliases: CD2BP2; KIAA1178
Entrez Gene ID: (Human) 10421
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