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Invitrogen
SPNS1 Polyclonal Antibody
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FIGURE: 1 / 7
SPNS1 Antibody (PA5-59813) in IHC (P)
Immunohistochemistry analysis of SPNS1 in human lung, pancreas, placenta and testis. Samples were incubated with SPNS1 polyclonal antibody (Product # PA5-59813). Shows similar protein distribution across tissues to independent SPNS1 antibody (Product # PA5-60188) (B).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-59813
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MAGSDTAPFL SQADDPDDGP VPGTPGLPGS TGNPKSEEPE VPDQEGLQRI TGLSPGRS
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.
Target Information
SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily. SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death. The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: similar to Drosophila spinster protein; SPIN1; solute carrier family 63 member 1; sphingolipid transporter 1 (putative); spinster homolog 1; spinster-like protein 1; SPNS sphingolipid transporter 1 (putative); unnamed protein product
Gene Aliases: HSpin1; LAT; nrs; PP2030; SLC62A1; SLC63A1; SPIN1; SPINL
UniProt ID: (Human) Q9H2V7
Entrez Gene ID: (Human) 83985
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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