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          • Primary Antibodies ›
          • HSD17B8 Antibodies

          Invitrogen

          HSD17B8 Polyclonal Antibody

          Advanced Verification
          View all (12) HSD17B8 antibodies

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          Cite HSD17B8 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (4)
          • Advanced Verification (1)
          HSD17B8 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.
          HSD17B8 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          HSD17B8 Antibody (PA5-59882) in IHC

          Immunohistochemical staining of HSD17B8 in human parathyroid gland and testis tissues using HSD17B8 Polyclonal Antibody (Product # PA5-59882). Corresponding HSD17B8 RNA-seq data are presented for the same tissues. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

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          HSD17B8 Antibody in Immunohistochemistry (IHC)
          HSD17B8 Antibody in Immunohistochemistry (IHC)
          HSD17B8 Antibody in Immunohistochemistry (IHC)
          HSD17B8 Antibody in Western Blot (WB)
          HSD17B8 Antibody
          HSD17B8 Polyclonal Antibody

          Product Details

          PA5-59882

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000-1:2,500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human HSD17B8. Recombinant protein control fragment (Product #RP-99282).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Amount

          50 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2642568

          Product Specific Information

          Immunogen sequence: GQTNYAASKA GVIGLTQTAA RELGRHGIRC NSVLPGFIAT PMTQKVPQKV VDKITEMIPM GHLGDPEDVA DVVAFLASED SGY

          Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

          Target Information

          NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-HSD 8; 17-beta-hydroxysteroid dehydrogenase 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; estrogen 17-oxidoreductase; H FABGL; KAR alpha subunit; ke-6; Ke6; Protein Ke6; really interesting new gene 2 protein; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8

          View more View less

          Gene Aliases: D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; HSD17B8; KE6; RING2; SDR30C1

          View more View less

          UniProt ID: (Human) Q92506

          View more View less

          Entrez Gene ID: (Human) 7923

          View more View less

          Function(s)
          estradiol 17-beta-dehydrogenase activity protein binding oxidoreductase activity testosterone dehydrogenase (NAD+) activity quinone binding NADH binding (3R)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
          Process(es)
          lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process steroid biosynthetic process estrogen biosynthetic process androgen metabolic process estrogen metabolic process protein heterotetramerization
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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