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          • Primary Antibodies ›
          • CSH1 Antibodies

          Invitrogen

          CSH1 Polyclonal Antibody

          View all (9) CSH1 antibodies

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          Cite CSH1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          CSH1 Antibody in Immunohistochemistry (IHC)
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          CSH1 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CSH1 Antibody (PA5-60480) in IHC

          Immunohistochemical staining of CSH1 in human pituitary gland using a CSH1 Polyclonal Antibody (Product # PA5-60480) shows strong cytoplasmic positivity in cells in anterior lobe. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          CSH1 Antibody in Immunohistochemistry (IHC)
          CSH1 Polyclonal Antibody

          Product Details

          PA5-60480

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000-1:2,500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human CSH1. Recombinant protein control fragment (Product #RP-104361).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          20 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2640195

          Product Specific Information

          Immunogen sequence: SHNHDALLKN YGLLYCFRKD MDKVETFLRM VQCRSVEGSC GF

          Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 58%.

          Target Information

          The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Choriomammotropin; chorionic somatomammotropin; chorionic somatomammotropin A; Chorionic somatomammotropin hormone 1; Chorionic somatomammotropin hormone 2; chorionic somatomammotropin-1; growth hormone B3; hPL; Lactogen; PL; Placental lactogen; unnamed protein product

          View more View less

          Gene Aliases: CS-1; CSA; CSH1; CSMT; GHB3; hCS-1; hCS-A; PL

          View more View less

          UniProt ID: (Human) P0DML2

          View more View less

          Entrez Gene ID: (Human) 1442

          View more View less

          Function(s)
          growth hormone receptor binding hormone activity protein binding growth factor activity metal ion binding
          Process(es)
          response to nutrient levels positive regulation of JAK-STAT cascade animal organ development growth hormone receptor signaling pathway
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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