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Invitrogen
GCP3 Polyclonal Antibody
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Product Details
PA5-60549
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GCP3. Recombinant protein control fragment (Product #RP-97940).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LLSVLHSQLQ LEDDQGVNLG LESSLTLRRL LVWTYDPKIR LKTLAALVDH CQGRKGGELA SAVHAYTKTG DPYMRSLVQH ILSLVSHPVL SFLYRWIYDG ELEDTYHEFF VASDPTVKT
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
Target Information
The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP3 (gamma-tubulin complex component 3), also known as TUBGCP3 or SPBC98, localizes to the centrosome and is an ubiquitously expressed 907 amino acid member of the gamma-Tubulin complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: component of cytoplasmic gamma-tubulin complex; Gamma-ring complex protein 104 kDa; Gamma-tubulin complex component 3; GCP-3; h104p; hGCP3; hGrip104; hSpc98; Spindle pole body protein Spc98 homolog; tubulin gamma complex associated protein 3; unnamed protein product
Gene Aliases: 104p; ALP6; GCP3; Grip104; SPBC98; Spc98; Spc98p; TUBGCP3
UniProt ID: (Human) Q96CW5
Entrez Gene ID: (Human) 10426
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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