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Invitrogen
DIP13B Polyclonal Antibody
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Product Details
PA5-60553
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DIP13B. Recombinant protein control fragment (Product #RP-97756).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KICYAINLGK EIIEVQKDPE ALAQLMLSIP LTNDGKYVLL NDQPDDDDGN PNEHRGAESE A
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.
Target Information
Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adapter protein containing PH domain, PTB domain and leucine zipper motif 2; adaptor protein; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2; DCC-interacting protein 13-beta; DIP13 beta; Dip13-beta; unnamed protein product
Gene Aliases: APPL2; DIP13B
UniProt ID: (Human) Q8NEU8
Entrez Gene ID: (Human) 55198
diet induced thermogenesis
protein import into nucleus
signal transduction
transforming growth factor beta receptor signaling pathway
cold acclimation
regulation of fibroblast migration
signaling
adiponectin-activated signaling pathway
regulation of toll-like receptor 4 signaling pathway
cellular response to hepatocyte growth factor stimulus
homeostatic process
glucose homeostasis
regulation of innate immune response
negative regulation of fatty acid oxidation
negative regulation of glucose import
negative regulation of neurogenesis
protein homotetramerization
positive regulation of phagocytosis, engulfment
positive regulation of cold-induced thermogenesis
negative regulation of cytokine production involved in inflammatory response
negative regulation of cellular response to insulin stimulus
positive regulation of macropinocytosis
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of G1/S transition of mitotic cell cycle
negative regulation of neural precursor cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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