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Invitrogen
ZIP13 Polyclonal Antibody
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Product Details
PA5-60566
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ZIP13. Recombinant protein control fragment (Product #RP-99870).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TATACRLDNK ESESWGALLS GERLDT
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 88%.
Target Information
The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LIV-1 subfamily of ZIP zinc transporter 9; LIV-1 subfamily of ZIP zinc transporters human member 9; LZT-Hs9; solute carrier family 39 (metal ion transporter), member 13; solute carrier family 39 (zinc transporter), member 13; Solute carrier family 39 member 13; unnamed protein product; zinc transporter 13; Zinc transporter ZIP13; ZIP-13; Zrt- and Irt-like protein 13; ZRT/IRT-like protein 13
Gene Aliases: EDSSPD3; LZT-Hs9; SCDEDS; SLC39A13; ZIP13
UniProt ID: (Human) Q96H72
Entrez Gene ID: (Human) 91252
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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