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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: RHQLQQRRKE KERRVAREAL RGEVGHLGLA LEELQAQVQA TSTQLALEEL RAQLQEVRAH LCLRDP
Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 35%.
The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-methylglutaconic aciduria type III; FLJ22187; FLJ25932; MGC75494; OPA3 outer mitochondrial membrane lipid metabolism regulator; optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia); Optic atrophy 3 (Iraqi-Jewish 'optic atrophy plus'); unnamed protein product
Gene Aliases: MGA3
UniProt ID: (Human) Q9H6K4
Entrez Gene ID: (Human) 80207
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