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Invitrogen
TTC5 Polyclonal Antibody
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Product Details
PA5-60894
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TTC5. Recombinant protein control fragment (Product #RP-100595).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GALTHCRNKV SLQNLSMVLR QLRTDTEDEH SHHVMDSVRQ AKLAVQMDVH DGRSWYILGN SYLSLYFSTG QNPKISQQAL SAYAQAEKVD RKASSNPDL
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Target Information
Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Strap; Stress-responsive activator of p300; Tetratricopeptide repeat protein 5; TPR repeat protein 5
Gene Aliases: Strap; TTC5
UniProt ID: (Human) Q8N0Z6
Entrez Gene ID: (Human) 91875
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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