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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • UBXN2B Antibodies

          Invitrogen

          UBXN2B Polyclonal Antibody

          View all (6) UBXN2B antibodies

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          Cite UBXN2B Polyclonal Antibody

          • Antibody Testing Data (2)
          UBXN2B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          UBXN2B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          UBXN2B Antibody (PA5-60969) in ICC/IF

          Immunofluorecent analysis of UBXN2B in human cell line A-431 using UBXN2B Polyclonal Antibody (Product # PA5-60969). Staining shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          UBXN2B Antibody in Immunocytochemistry (ICC/IF)
          UBXN2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          UBXN2B Polyclonal Antibody

          Product Details

          PA5-60969

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human UBXN2B. Recombinant protein control fragment (Product #RP-100343).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2649219

          Product Specific Information

          Immunogen sequence: GEQERRSSGP RPPSARDLQL ALAELYEDEV KCKSSKSNRP KATVFKSPRT PPQRFYSSEH EYSGLNIVRP S

          Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 75%.

          Target Information

          UBXD2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain. UBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: NSFL1 cofactor p37; p97 cofactor p37; UBX domain-containing protein 2B

          View more View less

          Gene Aliases: p37; UBXN2B

          View more View less

          UniProt ID: (Human) Q14CS0

          View more View less

          Entrez Gene ID: (Human) 137886

          View more View less

          Function(s)
          protein binding ubiquitin binding protein-binding activity modulator
          Process(es)
          Golgi organization nuclear envelope reassembly proteasome-mediated ubiquitin-dependent protein catabolic process membrane fusion
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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