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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: IIAKMKGTFV ERDRKREKRK PKSQETPATK KAVQGGGATP VVGAVQGPVP GMPPMTQAPR IMHHMPGQPP YMP
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: U1 small nuclear ribonucleoprotein A; U1 snRNP A
Gene Aliases: SNRPA
Entrez Gene ID: (Human) 6626
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