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Invitrogen
NHEDC2 Polyclonal Antibody
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Product Details
PA5-61400
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NHEDC2. Recombinant protein control fragment (Product #RP-96709).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PSTGMNYTPS MHQEAQEETV MKLKGIDANE PTEGSILLKS SEKKLQETPT EANHVQR
Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 46%.
Target Information
Electroneutral exchange of protons for Na(+) and Li(+) across the inner mitochondrial membrane. Contributes to the organellar volume homeostasis. Required for osteoclast differentiation and bone resorption activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: mitochondrial Na(+)/H(+) exchanger NHA2; mitochondrial sodium/hydrogen exchanger 9B2; mitochondrial sodium/hydrogen exchanger NHA2; Na(+)/H(+) exchanger NHA2; Na(+)/H(+) exchanger-like domain-containing protein 2; Na+/H+ exchanger domain containing 2; NHE domain-containing protein 2; Sodium/hydrogen exchanger 9B2; Sodium/hydrogen exchanger-like domain-containing protein 2; Solute carrier family 9 subfamily B member 2; solute carrier family 9, subfamily B (cation proton antiporter 2), member 2; solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2; unnamed protein product
Gene Aliases: NHA2; NHE10; NHEDC2; SLC9B2
UniProt ID: (Human) Q86UD5
Entrez Gene ID: (Human) 133308
ion transport
cation transport
sodium ion transport
lithium ion transport
sperm motility
ion transmembrane transport
sodium ion transmembrane transport
sodium ion homeostasis
transmembrane transport
regulation of insulin secretion involved in cellular response to glucose stimulus
clathrin-mediated endocytosis
inorganic cation transmembrane transport
hydrogen ion transmembrane transport
positive regulation of osteoclast development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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