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          • Primary Antibodies ›
          • KBTBD3 Antibodies

          Invitrogen

          KBTBD3 Polyclonal Antibody

          View all (6) KBTBD3 antibodies

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          Cite KBTBD3 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          KBTBD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          KBTBD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 1

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          KBTBD3 Antibody (PA5-61495) in IHC (P)

          Immunohistochemical analysis of KBTBD3 in human smooth muscle using KBTBD3 Polyclonal Antibody (Product # PA5-61495) shows strong cytoplasmic positivity in smooth muscle cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          KBTBD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KBTBD3 Polyclonal Antibody

          Product Details

          PA5-61495

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:50
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human KBTBD3. Recombinant protein control fragment (Product #RP-97514).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Amount

          5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2642893

          Product Specific Information

          Immunogen sequence: IMDAIKCVQG SGGLFPDARP STTEKYIFIH KTEENGENQY TFCYNIKSDS WKILPQSHLI DLPGSSLSSY GEKIFLTGGC KGKCCRTVRL HIAESYHDAT DQTWCY

          Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

          Target Information

          The BTB (Broad-Complex, Tram track and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KBTBD3 (kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain and five kelch repeats. The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: BTB and kelch domain containing 3; BTB and kelch domain-containing protein 3; epididymis secretory sperm binding protein; kelch repeat and BTB (POZ) domain containing 3; Kelch repeat and BTB domain-containing protein 3; unnamed protein product

          View more View less

          Gene Aliases: BKLHD3; KBTBD3

          View more View less

          UniProt ID: (Human) Q8NAB2

          View more View less

          Entrez Gene ID: (Human) 143879

          View more View less

          Function(s)
          protein binding, bridging involved in substrate recognition for ubiquitination
          Process(es)
          proteasome-mediated ubiquitin-dependent protein catabolic process
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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