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Invitrogen
BLOC1S2 Polyclonal Antibody
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Product Details
PA5-61647
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human BLOC1S2. Recombinant protein control fragment (Product #RP-100818).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AAEGVLATRS DEPARDDAAV ETAEEAKEP
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 86%.
Target Information
BLOC1S2 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 11 kDa centrosome associated protein; Biogenesis of lysosome-related organelles complex 1 subunit 2; BLOC-1 subunit 2; BLOS2; Ceap-11; centrosomal 10 kDa protein; centrosome protein oncogene; Centrosome-associated protein; RP11-316M21.4; unnamed protein product
Gene Aliases: BLOC1S2; BLOS2; BORCS2; CEAP; CEAP11
UniProt ID: (Human) Q6QNY1
Entrez Gene ID: (Human) 282991
microtubule nucleation
anterograde axonal transport
positive regulation of cell proliferation
extrinsic apoptotic signaling pathway via death domain receptors
endosomal transport
neuron projection development
lysosome localization
melanosome organization
positive regulation of transcription, DNA-templated
anterograde synaptic vesicle transport
regulation of endosome size
platelet dense granule organization
regulation of lysosome size
organelle transport along microtubule
mitochondrial outer membrane permeabilization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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