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Invitrogen
GAL Polyclonal Antibody
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Product Details
PA5-62069
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
C. elegans
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GAL. Recombinant protein control fragment (Product #RP-101186).
Conjugate
Form
Liquid
Concentration
0.40 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GPHAVGNHRS FSDKNGLTSK RELRPEDDMK PGSFDRSIPE NNIMRTIIEF LSFLHLKEAG ALDRLLDLPA AASSEDIERS
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 65%.
Target Information
Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion. [Uniprot]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Galanin peptides; galanin prepropeptide; galanin-message-associated peptide; galanin-related peptide; galanin/GMAP prepropeptide; MGC40167
Gene Aliases: ETL8; GAL; GAL-GMAP; GAL1; GALN; GLNN; GMAP
UniProt ID: (Human) P22466
Entrez Gene ID: (Human) 51083
inflammatory response
neuropeptide signaling pathway
nervous system development
feeding behavior
protein kinase A signaling
cAMP-mediated signaling
insulin secretion
regulation of glucocorticoid metabolic process
response to insulin
response to immobilization stress
response to drug
positive regulation of apoptotic process
response to estrogen
positive regulation of transcription from RNA polymerase II promoter
negative regulation of lymphocyte proliferation
positive regulation of cortisol secretion
positive regulation of catagen
positive regulation of large conductance calcium-activated potassium channel activity
negative regulation of root hair elongation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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