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Invitrogen
TUSC3 Polyclonal Antibody
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Product Details
PA5-62109
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TUSC3. Recombinant protein control fragment (Product #RP-103752).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GQKKKENLLA EKVEQLMEWS SRRSIFRMNG DKFRKFI
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Target Information
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 39 kDa encoded by N33; alternatively spliced; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3; Magnesium uptake/transporter TUSC3; MGC13453; Oligosaccharyl transferase subunit TUSC3; oligosaccharyltransferase 3 homolog A; Protein N33; putative prostate cancer tumor suppressor; Tumor suppressor candidate 3
Gene Aliases: D8S1992; M33; MagT2; MRT22; MRT7; N33; OST3A; SLC58A2; TUSC3
UniProt ID: (Human) Q13454
Entrez Gene ID: (Human) 7991
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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