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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: HSHESQDLRV IDFNCTTSSV SSALANTKDS PVLIDFFEDT ERYRKQANKA LEKYKEENDD FASFRVDRIE RVARVRGG
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 71%.
HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp779H1622; Histidine-proline-rich glycoprotein; Histidine-rich glycoprotein; HPRG
Gene Aliases: HRG
Entrez Gene ID: (Human) 3273
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