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Invitrogen
CNOT8 Polyclonal Antibody
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Product Details
PA5-62399
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CNOT8. Recombinant protein control fragment (Product #RP-101388).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: CGRLYGLGTG VAQKQNEDVD SAQEKMSILA IINNMQQ
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 97%.
Target Information
CNOT8 (CCR4-NOT transcription complex subunit 8), also known as CALIF or POP2, is a 292 amino acid protein that localizes to both the nucleus and the cytoplasm and functions as part of the CCR-NOT complex. Expressed ubiquitously, CNOT8 plays a role in transcriptional regulation for a diverse set of processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAF1-like protein; CAF1-like protein; CCR4-NOT complex subunit; Caf1b; CAF2; CALIFp; CCR4-associated factor 8; CCR4-NOT transcription complex subunit 8; h CAF1-like protein; PGK promoter directed over production; unnamed protein product
Gene Aliases: CAF1; Caf1b; CALIF; CNOT8; hCAF1; POP2
UniProt ID: (Human) Q9UFF9
Entrez Gene ID: (Human) 9337
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
regulation of translation
positive regulation of cell proliferation
gene silencing by RNA
mRNA cleavage involved in gene silencing by miRNA
positive regulation of mRNA catabolic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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