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          • Primary Antibodies ›
          • MLX Antibodies

          Invitrogen

          MLX Polyclonal Antibody

          View all (13) MLX antibodies

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          Cite MLX Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          MLX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          MLX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MLX Antibody (PA5-62677) in IHC (P)

          Immunohistochemical analysis of MLX in human cerebellum using MLX Polyclonal Antibody (Product # PA5-62677) shows strong cytoplasmic positivity in Purkinje cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          MLX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MLX Polyclonal Antibody

          Product Details

          PA5-62677

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human MLX. Recombinant protein control fragment (Product #RP-103135).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2644005

          Product Specific Information

          Immunogen sequence: EEVSTLRKDV TALKIMKVNY EQIVKAHQDN PHEGEDQVSD QVKFNVFQGI MDSLFQSFNA SISVASFQEL SA

          Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

          Target Information

          The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: bHLHd13; BigMax protein; Class D basic helix-loop-helix protein 13; homodimerizes and heterodimerizes with the transcription repressor Rox; homodimerizes and heterodimerizes with the transcriptional repressor Rox; MAX-like bHLHZIP protein; Max-like protein X; MLX; MLX, MAX dimerization protein; Protein BigMax; Transcription factor-like protein 4; unnamed protein product

          View more View less

          Gene Aliases: BHLHD13; MAD7; MLX; MXD7; TCFL4; TF4

          View more View less

          UniProt ID: (Human) Q9UH92

          View more View less

          Entrez Gene ID: (Human) 6945

          View more View less

          Function(s)
          RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein homodimerization activity protein heterodimerization activity protein dimerization activity RNA polymerase II sequence-specific DNA binding transcription factor binding sequence-specific double-stranded DNA binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter
          It has to be done as per old AB suggested Products section.

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