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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SKWFSESGKL VTKMFQKIQD LIDDKDALVF VLIDEVESLT AARNACRAGT EPSDAIRVVN AVLTQIDQIK RHSNVVILTT SNITEKIDVA FVDRADIKQY IGPPSA
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 (thyroid hormone receptor interactor 13), also called 16E1BP, is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 16E1-BP; Human papillomavirus type 16 E1 protein-binding protein; Pachytene checkpoint protein 2 homolog; Thyroid hormone receptor interactor 13; Thyroid receptor-interacting protein 13; TR-interacting protein 13
Gene Aliases: PCH2; TRIP13
Entrez Gene ID: (Human) 9319
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