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Invitrogen
ABCA9 Polyclonal Antibody
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Product Details
PA5-63027
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ABCA9. Recombinant protein control fragment (Product #RP-101389).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FWFQHGRANH VVLENETDSD PTPNDCFEP
Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 62%.
Target Information
ABCA9 (ATP-binding cassette, sub-family A (ABC1), member 9) is a 1,624 amino acid protein belonging to the ABC transporter superfamily and the ABCA family. The ABC1 subfamily is the only major ABC subfamily exclusive to multicellular eukaryotes. Ubiquitously expressed, with high expression in heart, brain and fetal tissues, ABCA9 is a multi-pass membrane protein that contains two ABC transporter domains and exists as five alternatively spliced isoforms. ABCA9 exhibits membrane subcellular localization and may play a role in monocyte differentiation and lipid homeostasis. ABCA9 is up-regulated during monocyte differentiation into macrophages and down-regulated by cholesterol loading of macrophages. Spanning 85 kb, ABCA9 contains 39 exons, with a non-coding first exon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-binding cassette A9; ATP-binding cassette sub-family A member 9; ATP-binding cassette, sub-family A (ABC1), member 9; DKFZp686F2450; MGC75415
Gene Aliases: ABCA9; EST640918
UniProt ID: (Human) Q8IUA7
Entrez Gene ID: (Human) 10350
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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