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Invitrogen
MRPL28 Polyclonal Antibody
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Product Details
PA5-63149
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MRPL28. Recombinant protein control fragment (Product #RP-103222).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
40 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PVWLWKRLQL REGICSRLPG HYLRSLEEER TPTPVHYRPH GAKFKINPKN GQRERVEDVP IPIYFPPESQ RGLWGGEGWI LGQIYANND
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 80%.
Target Information
MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein that belongs to the ribosomal protein L28P family. MRP-L28 potentially represents an important therapeutic reagent for HLA-A24 (A24) patients as this antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290, which targets the A24 serotype. HLAA24 (A24) is an HLA-A serotype that identifies the more common HLA-A24 gene products. A24 is a split antigen that is also recognized by the A9 broad antigen type and the similar A23 types. A24 is common in Austronesia and has one of the highest A allele frequencies for a number of peoples, including Papua New Guineans, indigeonous Taiwanese (eastern tribals), Yupik and Greenland Eskimos. MRP-L28 is found in a variety of normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung and retinal tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 39S ribosomal protein L28, mitochondrial; HGNC6756; L28mt; Large ribosomal subunit protein bL28m; MAAT 1; Melanoma antigen p15; melanoma-associated antigen recognised by cytotoxic T lymphocytes; Melanoma-associated antigen recognized by T-lymphocytes; MGC8499; mitochondrial large ribosomal subunit protein bL28m; MRP L28; MRP-L28; MRPL 28; MRPL28; unnamed protein product
Gene Aliases: bL28m; MAAT1; MRPL28; p15
UniProt ID: (Human) Q13084
Entrez Gene ID: (Human) 10573
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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