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Invitrogen
DDX52 Polyclonal Antibody
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Product Details
PA5-63257
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DDX52. Recombinant protein control fragment (Product #RP-93272).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KFDTRRFSAD AARFQIGKRK YDFDSSEVLQ GLDFFGNKKS VPGVCGASQT HQKPQNGEKK EESLTERKRE QSKKKRKTMT SEIAS
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 60%.
Target Information
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent RNA helicase ROK1-like; DEAD (Asp-Glu-Ala-Asp) box polypeptide 52; DEAD box protein 52; DEAD-box helicase 52; Probable ATP-dependent RNA helicase DDX52; unnamed protein product
Gene Aliases: DDX52; HUSSY-19; HUSSY19; ROK1
UniProt ID: (Human) Q9Y2R4
Entrez Gene ID: (Human) 11056
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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