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          • Primary Antibodies ›
          • CBX7 Antibodies

          Invitrogen

          CBX7 Polyclonal Antibody

          View all (13) CBX7 antibodies

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          Cite CBX7 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          CBX7 Antibody in Immunocytochemistry (ICC/IF)
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          CBX7 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          CBX7 Antibody (PA5-63310) in ICC/IF

          Immunofluorecent analysis of CBX7 in human cell line U-2 OS using CBX7 Polyclonal Antibody (Product # PA5-63310). Staining shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          CBX7 Antibody in Immunocytochemistry (ICC/IF)
          CBX7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          CBX7 Polyclonal Antibody

          Product Details

          PA5-63310

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human CBX7. Recombinant protein control fragment (Product #RP-103259).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Amount

          50 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2639335

          Product Specific Information

          Immunogen sequence: KPKRLLLQRL YSMDLRSSHK AKGKEKLCFS LTCPLGSGSP EGVVKAGAPE LVDKG

          Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 28%.

          Target Information

          The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: CBX7

          View more View less

          UniProt ID: (Human) O95931

          View more View less

          Entrez Gene ID: (Human) 23492

          View more View less

          Function(s)
          protein binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter heterochromatin assembly negative regulation of transcription, DNA-templated
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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