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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TBL1Y Antibodies

          Invitrogen

          TBL1Y Polyclonal Antibody

          View all (5) TBL1Y antibodies

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          Cite TBL1Y Polyclonal Antibody

          • Antibody Testing Data (1)
          TBL1Y Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          TBL1Y Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          TBL1Y Antibody (PA5-63811) in IHC (P)

          Immunohistochemical analysis of TBL1Y in human prostate using TBL1Y Polyclonal Antibody (Product # PA5-63811) shows strong nuclear positivity in glandular cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          TBL1Y Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TBL1Y Polyclonal Antibody

          Product Details

          PA5-63811

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000-1:2,500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein fragment of Human TBL1Y (Product #RP-99599).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2648293

          Product Specific Information

          Immunogen sequence: QASAAATEAS AMAKAATMTP AAISQQ

          Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 58%.

          Target Information

          The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: F-box-like/WD repeat-containing protein TBL1Y; transducin beta-like 1; Transducin beta-like protein 1Y; Transducin-beta-like protein 1, Y-linked

          View more View less

          Gene Aliases: TBL1; TBL1Y

          View more View less

          UniProt ID: (Human) Q9BQ87

          View more View less

          Entrez Gene ID: (Human) 90665

          View more View less

          Function(s)
          transcription corepressor activity
          Process(es)
          transcription, DNA-templated regulation of transcription from RNA polymerase II promoter histone deacetylation negative regulation of nucleic acid-templated transcription
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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