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Invitrogen
SLC7A8 Polyclonal Antibody
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Product Details
PA5-63887
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLC7A8. Recombinant protein control fragment (Product #RP-104269).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: WQHKPKCFSD FIELLTLVSQ KMCVVVYPEV ERGSGTEEAN ED
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 79%.
Target Information
SLC7A8 is sodium-independent, high-affinity transport of large neutral amino acids. It has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. SLC7A8 also plays a role in basolateral (re)absorption of neutral amino acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hLAT2; integral membrane protein E16H; L-type amino acid transporter 2; Large neutral amino acids transporter small subunit 2; Light subunit of 4F2hc; solute carrier family 7 (amino acid transporter light chain, L system), member 8; solute carrier family 7 (amino acid transporter, L-type), member 8; solute carrier family 7 (cationic amino acid transporter, y+ system), member 8; Solute carrier family 7 member 8; unnamed protein product
Gene Aliases: LAT2; LPI-PC1; SLC7A8
UniProt ID: (Human) Q9UHI5
Entrez Gene ID: (Human) 23428
protein binding
organic cation transmembrane transporter activity
amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
L-amino acid transmembrane transporter activity
L-alanine transmembrane transporter activity
glycine transmembrane transporter activity
L-leucine transmembrane transporter activity
antiporter activity
thyroid hormone transmembrane transporter activity
toxin transporter activity
transmembrane transporter activity
peptide antigen binding
protein heterodimerization activity
amino acid transmembrane transport
amino acid transport
neutral amino acid transport
L-amino acid transport
glycine transport
leucine transport
tryptophan transport
valine transport
proline transmembrane transport
transmembrane transport
thyroid hormone transport
amino acid import across plasma membrane
transport across blood-brain barrier
L-leucine import across plasma membrane
L-alanine import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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