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Invitrogen
EXOC5 Polyclonal Antibody
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Product Details
PA5-63904
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EXOC5. Recombinant protein control fragment (Product #RP-100834).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TVLAKLIQNV FEIKLQSFVK EQLEECRKSD AEQYLKNLYD LYTRTTNLSS KLMEFNLGTD KQTF
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Target Information
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp666H126; Exocyst complex component 5; Exocyst complex component Sec10; hSec10; SEC10-like 1; unnamed protein product
Gene Aliases: EXOC5; HSEC10; PRO1912; SEC10; SEC10L1; SEC10P
UniProt ID: (Human) O00471
Entrez Gene ID: (Human) 10640
mitotic cytokinesis
establishment of planar polarity
exocytosis
post-Golgi vesicle-mediated transport
Golgi to plasma membrane transport
vesicle docking involved in exocytosis
protein transport
protein localization to plasma membrane
membrane fission
vesicle tethering involved in exocytosis
epithelial cell apoptotic process
non-motile cilium assembly
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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