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Invitrogen
ADH5 Polyclonal Antibody
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Product Details
PA5-63991
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ADH5. Recombinant protein control fragment (Product #RP-103909).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GGWKSVESVP KLVSEYMSKK IKVDEFVTHN LSFDEINKAF ELMHSGKSI
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 92%.
Target Information
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADH5; alcohol dehydrogenase (class III), chi polypeptide; Alcohol dehydrogenase 5; Alcohol dehydrogenase class chi chain; alcohol dehydrogenase class III; Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; epididymis secretory sperm binding protein Li 60p; FALDH; formaldehyde dehydrogenase; Glutathione-dependent formaldehyde dehydrogenase; S-(hydroxymethyl)glutathione dehydrogenase; S-nitrosoglutathione reductase; unnamed protein product
Gene Aliases: ADH-3; ADH5; ADHX; AMEDS; BMFS7; FALDH; FDH; GSH-FDH; GSNOR; HEL-S-60p
UniProt ID: (Human) P11766
Entrez Gene ID: (Human) 128
alcohol dehydrogenase (NAD) activity
fatty acid binding
zinc ion binding
electron carrier activity
oxidoreductase activity
formaldehyde dehydrogenase activity
identical protein binding
metal ion binding
S-(hydroxymethyl)glutathione dehydrogenase activity
S-nitrosoglutathione reductase activity
S-(hydroxymethyl)glutathione dehydrogenase NADP activity
S-(hydroxymethyl)glutathione dehydrogenase NAD activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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