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Invitrogen
NUCKS1 Polyclonal Antibody
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Product Details
PA5-64016
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NUCKS1. Recombinant protein control fragment (Product #RP-103854).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MEDDDDSDYG SSKKKNKKMV KKSKPERKEK KMPKPRLKAT VTPSPVKGKG
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 100%.
Target Information
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: nuclear casein kinase and cyclin-dependent kinase substrate 1; Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1; nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate; P1; potential LAG1 interactor
Gene Aliases: JC7; NUCKS; NUCKS1
UniProt ID: (Human) Q9H1E3
Entrez Gene ID: (Human) 64710
double-strand break repair via homologous recombination
cellular glucose homeostasis
regulation of DNA replication
chromatin organization
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
release from viral latency
replication fork processing
gene conversion
interstrand cross-link repair
positive regulation by host of viral transcription
positive regulation by host of viral genome replication
modulation by host of viral molecular function
positive regulation of transcription from RNA polymerase II promoter
regulation of insulin receptor signaling pathway
positive regulation of insulin receptor signaling pathway
regulation of DNA strand elongation
cellular response to X-ray
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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