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Invitrogen
NFE2L1 Polyclonal Antibody
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Product Details
PA5-64222
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NFE2L1. Recombinant protein control fragment (Product #RP-103600).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LNLERDVEDL QRDKARLLRE KVEFLRSLRQ MKQKVQSLYQ EVFGRLRDEN GRPYSPSQYA LQYAGDGSVL LIP
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 51%.
Target Information
This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official symbol of NRF1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endoplasmic reticulum membrane sensor NFE2L1; LCR-F1; Locus control region-factor 1; NF-E2-related factor 1; NFE2-related factor 1; Nuclear factor erythroid 2-related factor 1; nuclear factor, erythroid 2 like 1; Nuclear factor, erythroid derived 2, like 1; Protein NRF1, p120 form; TCF-11; transc; Transcription factor 11; transcription factor 11 (basic leucine zipper type); transcription factor HBZ17; transcription factor LCR-F1; unnamed protein product
Gene Aliases: HBZ17; LCR-F1; NFE2L1; NRF-1; NRF1; TCF11
UniProt ID: (Human) Q14494
Entrez Gene ID: (Human) 4779
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
lipid binding
cholesterol binding
protein domain specific binding
identical protein binding
macromolecular complex binding
protein heterodimerization activity
promoter-specific chromatin binding
negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
fructose 6-phosphate metabolic process
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
lipid metabolic process
glutathione metabolic process
heme biosynthetic process
regulation of mitotic nuclear division
steroid metabolic process
cholesterol metabolic process
anatomical structure morphogenesis
regulation of gene expression
regulation of glucose metabolic process
regulation of lipid metabolic process
regulation of fatty acid metabolic process
cellular homeostasis
spinal cord motor neuron differentiation
glial cell fate commitment
erythrocyte differentiation
cellular response to oxidative stress
response to endoplasmic reticulum stress
cholesterol homeostasis
cysteine transport
cell redox homeostasis
positive regulation of transcription from RNA polymerase II promoter
regulation of inflammatory response
glucose 6-phosphate metabolic process
lipid homeostasis
regulation of proteasomal protein catabolic process
cellular response to cold
cellular response to copper ion
cellular response to cholesterol
regulation of odontoblast differentiation
regulation of nucleus organization
regulation of response to endoplasmic reticulum stress
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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