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Invitrogen
PTGES2 Polyclonal Antibody
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Product Details
PA5-64984
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human PTGES2. Recombinant protein control fragment (Product #RP-104567).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AQDLHAERSAA QLSLSSRLQL TLYQYKTCPF CSKVRAFLDF HALPYQVVEV NPVRRAEIKF SSYRKVPILV AQEGESSQ
Highest antigen sequence identity to the following orthologs - mouse 89%, rat 91%.
Target Information
The PTGES2 gene encodes for the enzyme prostaglandin E synthase 2 (PTGES2), which is crucial for the biosynthesis of prostaglandin E2 (PGE2) from arachidonic acid. This enzyme operates downstream of the cyclooxygenase (COX) pathway, particularly interacting with COX-1 and COX-2 enzymes. PTGES2 is involved in various physiological and pathological processes by generating PGE2, which functions in inflammation, fever generation, and pain. Notably, PTGES2 is a membrane-associated protein and is distinct in its role compared to other prostaglandin synthases due to its specific functional and regulatory properties. Its activity is essential in fine-tuning the levels of PGE2 in tissues, impacting numerous signaling cascades, including those involved in immune responses and vascular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ14038; gamma-interferon-activated transcriptional element-binding factor 1; GATE-binding factor 1; membrane-associated prostaglandin E synthase 2; Membrane-associated prostaglandin E synthase-2; MGC11289; Microsomal prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; mPGE synthase-2; mPGES-2; Prostaglandin E synthase 2; Prostaglandin-H(2) E-isomerase; RP11-395P17.2; unnamed protein product
Gene Aliases: C9orf15; GBF-1; GBF1; mPGES-2; PGES2; PTGES2
UniProt ID: (Human) Q9H7Z7
Entrez Gene ID: (Human) 80142
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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