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Invitrogen
PACT Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-65134
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human PACT. Recombinant protein control fragment (Product #RP-105894).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MSQSRHRAEAP PLEREDSGTF SLGKMITAKP GKTPIQVLHE YGMKTKNIPV YECERSDVQI HVPTFTFRV
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 96%.
Target Information
PRKRA appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor. It activates EIF2AK2 in the absence of double-stranded RNA (dsRNA).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dsRNA-binding protein; PKR interacting protein; PKR-associated protein X; PKR-associating protein X; PRKRA; protein activator of the interferon-induced protein kinase; protein kinase, interferon-inducible double-stranded RNA-dependent activator; unnamed protein product
Gene Aliases: DYT16; HSD14; PACT; RAX
UniProt ID: (Human) O75569
Entrez Gene ID: (Human) 8575
immune response
negative regulation of cell proliferation
response to virus
production of siRNA involved in RNA interference
pre-miRNA processing
production of miRNAs involved in gene silencing by miRNA
protein stabilization
regulation of production of small RNA involved in gene silencing by RNA
small RNA loading onto RISC
antiviral innate immune response
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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