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Invitrogen
DLX1 Polyclonal Antibody
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Product Details
PA5-65154
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human DLX1. Recombinant protein control fragment (Product #RP-96565).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MTMTTMPESLN SPVSGKAVFM EFGPPNQQMS PSPMSHGHYS MHCLHSAGHS QPDGAYSSAS SFSRPLGYPY VNSVS
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
Target Information
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-beta superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: distal-less homeo box 1; Homeobox protein DLX-1
Gene Aliases: DLX1
UniProt ID: (Human) P56177
Entrez Gene ID: (Human) 1745
negative regulation of transcription from RNA polymerase II promoter
proximal/distal pattern formation
subpallium development
hippocampus development
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
cerebral cortex GABAergic interneuron fate commitment
odontogenesis of dentin-containing tooth
negative regulation of neuron apoptotic process
negative regulation of Notch signaling pathway
embryonic skeletal system development
negative regulation of oligodendrocyte differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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