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Invitrogen
COH1 Polyclonal Antibody
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Product Details
PA5-65371
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human COH1. Recombinant protein control fragment (Product #RP-104778).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PSVIKIHTLVE SLKLSITDQQ LPMFIRIMQL GIALYYGEIG NFKEGEIEDL TCHNKDMLGN ITGSEDETR
Highest antigen sequence identity to the following orthologs - mouse 83%, rat 27%.
Target Information
COH1 (Cohen syndrome protein 1), also known as VPS13B (vacuolar protein sorting-associated protein 13B) or CHS1, belongs to the VPS13 family and may function in vesicle-mediated transport and sorting of proteins within the cell. COH1 is widely expressed and multiple alternatively spliced transcript variants have been observed. Mutations in this gene have been associated with Cohen syndrome. COH1 is a Golgi-localized peripheral membrane protein and plays a critical role in Golgi (re)assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bridge-like lipid transfer protein family member 5B; Cohen syndrome protein 1; Intermembrane lipid transfer protein VPS13B; unnamed protein product; Vacuolar protein sorting-associated protein 13B
Gene Aliases: BLTP5B; CHS1; COH1; KIAA0532; VPS13B
UniProt ID: (Human) Q7Z7G8
Entrez Gene ID: (Human) 157680
acrosome assembly
lipid transport
Golgi organization
nervous system development
central nervous system development
brain development
muscle organ development
memory
vesicle-mediated transport
dentate gyrus development
neuron projection development
slow endocytic recycling
social behavior
multicellular organism growth
maintenance of lens transparency
head morphogenesis
adipose tissue development
Golgi reassembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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