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          • Primary Antibodies ›
          • DAZAP2 Antibodies

          Invitrogen

          DAZAP2 Polyclonal Antibody

          View all (5) DAZAP2 antibodies

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          Cite DAZAP2 Polyclonal Antibody

          Additional Information:

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          • Antibody Testing Data (1)
          DAZAP2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          DAZAP2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          DAZAP2 Antibody (PA5-65420) in ICC/IF

          Immunofluorescent staining of DAZAP2 in human cell line MCF7 shows localization to nuclear speckles. Samples were probed using a DAZAP2 Polyclonal Antibody (Product # PA5-65420). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          DAZAP2 Antibody in Immunocytochemistry (ICC/IF)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          DAZAP2 Polyclonal Antibody

          Product Details

          PA5-65420

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human DAZAP2. Recombinant protein control fragment (Product #RP-106103).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Amount

          5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2663328

          Product Specific Information

          Immunogen sequence: GASLYLPMAQS VAVGPLGSTI PMAYYPVGPI YPPGSTVLVE GGYDAGARFG AGATAGNIPP PPPGC

          Highest antigen sequence identity to the following orthologs - mouse 98%, rat 95%.

          Target Information

          DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: deleted in azoospermia associated protein 2; KIAA0058; proline-rich transcript in brain; proline-rich transcript in brain protein; proline-rich transcript, brain-expressed protein; unnamed protein product

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          Gene Aliases: PRTB

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          UniProt ID: (Human) Q15038

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          Entrez Gene ID: (Human) 9802

          View more View less

          Function(s)
          p53 binding transcription coactivator activity protein binding receptor tyrosine kinase binding mitogen-activated protein kinase kinase kinase binding ubiquitin protein ligase binding identical protein binding protein serine/threonine kinase activator activity WW domain binding protein serine/threonine kinase binding DNA-binding transcription factor binding
          Process(es)
          protein destabilization stress granule assembly positive regulation of transcription, DNA-templated
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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